I am trying to model cells flowing through a 3D microfluidic channel in comsol. I have been having issues getting the results to match what I see experimentally, but I am not sure what factors I am missing.
The velocity profile from creeping flow looks appropriate, but the particle tracing is not even close to what I've obtained experimentally. I assume that if the particles (cells) touch the bottom surface of the microfluidic channel that they stick; however none of the particles reach the bottom of the channel by the end of my simulation. Experimentally I see between 100 and 2000 cells attaching to that surface, depending on the conditions.
Any help would be greatly appreciated.
The file size is too large to upload, but I can share it via email if anyone thinks they can help.
The velocity profile from creeping flow looks appropriate, but the particle tracing is not even close to what I've obtained experimentally. I assume that if the particles (cells) touch the bottom surface of the microfluidic channel that they stick; however none of the particles reach the bottom of the channel by the end of my simulation. Experimentally I see between 100 and 2000 cells attaching to that surface, depending on the conditions.
Any help would be greatly appreciated.
The file size is too large to upload, but I can share it via email if anyone thinks they can help.
